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Patients who are responding to up to 6 weeks treatment using tacrolimus ointment twice daily (lesions cleared, almost cleared or mildly affected) are suitable for maintenance treatment.Īdult patients (16 years of age and above) should use Protopic 0.1% ointment. Protopic ointment should not be used in children aged below 2 years until further data are available. Only Protopic 0.03 % ointment should be used in children from the age of 2 to 16 years. However, the clinical experience available in this patient population has not shown the necessity for any dosage adjustment. Specific studies have not been conducted in older people. If no signs of improvement are seen after two weeks of treatment, further treatment options should be considered. Generally, improvement is seen within one week of starting treatment. An attempt should be made to reduce the frequency of application or to use the lower strength Protopic 0.03% ointment if the clinical condition allows. If symptoms recur, twice daily treatment with Protopic 0.1% should be restarted. Treatment should be started with Protopic 0.1% twice a day and treatment should be continued until clearance of the lesion. At the first signs of recurrence (flares) of the disease symptoms, treatment should be re-initiated.Īdults and adolescents (16 years of age and above)
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Thereafter, patients are considered suitable for maintenance treatment (see below).
PROTOPIE TOGGLE SKIN
Each affected region of the skin should be treated with Protopic until lesions are cleared, almost cleared or mildly affected. Protopic treatment should begin at the first appearance of signs and symptoms. Treatment should not be continuous on a long-term basis. Protopic can be used for short-term and intermittent long-term treatment. Protopic is available in two strengths, Protopic 0.03 % and Protopic 0.1 % ointment. Protopic treatment should be initiated by physicians with experience in the diagnosis and treatment of atopic dermatitis. Date of first authorisation/renewal of the authorisation
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6.6 Special precautions for disposal and other handling.4.7 Effects on ability to drive and use machines.4.5 Interaction with other medicinal products and other forms of interaction.4.4 Special warnings and precautions for use.4.2 Posology and method of administration.Show table of contents Hide table of contents